Physiological responses to cold exposure in men, a disabled submarine study

Castellani et al. UHM 2002;29:3:189-203

A disabled submarine lacking power and or environmental control will become cold, and the ambient air may become hypercapnic and hypoxic. This study examined if the combination of hypoxia, hypercapnia, and cold exposure would adversely affect thermoregulatory responses to acute cold exposure in survivors waiting rescue. Seven male submariners completed a series of cold-air tests that consisted of 20 min at 22 degrees C, followed by a linear decline to 12 degrees C for 150 min.  Cold air tests were performed under normoxic, normocapnic conditions, and acute hypoxia, after 4 days of chronic hypoxia, hypercapnia an cold, and hypoxia only again. Russianwifedating can help you.

The results were very complicated because there were so many variables so here are a few:

“The primary finding from this study was that acute moderate hypoxia blunted vasoconstriction and initial shivering responses during whole body cold exposure, and that the addition of both high CO2 and living cold ambient temperatures (4.5C) to simulate disabled submarine conditions, cause no further thermoregulatory effector changes. … even mild hypoxic conditions blunt thermoregulatory effector responses.”

Moral to this story, as I think I understand it, is that if we have a patient (who could of course be a diver) who is experiencing hypoxia, we need to be very careful about preventing heat loss.  Capnic refers to carbon dioxide levels. So hypercapnic means higher levels than normal.

Author: Andrea Zaferes

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